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Normal and malignant megakaryopoiesis

1 Oct 2011

Abstract excerpt

Megakaryopoiesis is the process by which bone marrow progenitor cells develop into mature megakaryocytes (MKs), which in turn produce platelets required for normal haemostasis. Over the past decade, molecular mechanisms that contribute to MK development and differentiation have begun to be elucidated. In this review, we provide an overview of megakaryopoiesis and summarise the latest developments in this field....

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PMID: 22018018
DOI: 10.1017/s1462399411002043

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