Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic and physical interactions between the yeast ELG1 gene and orthologs of the Fanconi anemia pathway.

Cell cycle (Georgetown, Tex.) - 15 May 2013

Singh Shivani, Shemesh Keren, Liefshitz Batia, Kupiec Martin

Abstract excerpt

Fanconi anemia (FA) is a human syndrome characterized by genomic instability and increased incidence of cancer. FA is a genetically heterogeneous disease caused by mutations in at least 15 different genes; several of these genes are conserved in the yeast Saccharomyces cerevisiae. Elg1 is also a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomal Proteins, Non-Histone
Share to DEAD-box RNA Helicases
Share to Fanconi Anemia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hydroxyurea

Share to Methyl Methanesulfonate

Share to Proliferating Cell Nuclear Antigen

Share to Sumoylation

Share to Two-Hybrid System Techniques

Source

Open in PubMed Open full text

Identifiers

PMID: 23624835
DOI: 10.4161/cc.24756
PMCID: PMC3680542

Genes

PCNA
CHL1
FANCM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23624835-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic and physical interactions between the yeast ELG1 gene and orthologs of the Fanconi anemia pathway.PMID 23624835Read ↗

Rad5-dependent DNA repair functions of the Saccharomyces cerevisiae FANCM protein homolog Mph1.Semantic proximity Read ↗

Role of Elg1 protein in double strand break repair.Semantic proximity Read ↗

Cellular and molecular consequences of defective Fanconi anemia proteins in replication-coupled DNA repair: mechanistic insights.Semantic proximity Read ↗

Elg1 forms an alternative RFC complex important for DNA replication and genome integrity.Semantic proximity Read ↗

Functional and physical interaction between the mismatch repair and FA-BRCA pathwaysSemantic proximity Read ↗

A structure-function analysis of the yeast Elg1 protein reveals the importance of PCNA unloading in genome stability maintenance.Semantic proximity Read ↗

Rad5 and Its Human Homologs, HLTF and SHPRH, Are Novel Interactors of Mismatch RepairSemantic proximity Read ↗

A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M.Semantic proximity Read ↗

Assessing the link between BACH1/FANCJ and MLH1 in DNA crosslink repair.Semantic proximity Read ↗

The ELG1 clamp loader plays a role in sister chromatid cohesion.Semantic proximity Read ↗

Interactions of Exo1p with components of MutLalpha in Saccharomyces cerevisiae.Semantic proximity Read ↗

A New Method, "Reverse Yeast Two-Hybrid Array" (RYTHA), Identifies Mutants that Dissociate the Physical Interaction Between Elg1 and Slx5.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.