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Article

Clinical implications of CYP2D6 genetic polymorphism during treatment with antipsychotic drugs.

Current drug targets - 1 Dec 2006

Dorado P, Berecz R, Peñas-Lledó E M, Cáceres M C, Llerena A

Abstract excerpt

CYP2D6 is described as the most relevant enzyme in the metabolism of many antipsychotic drugs. Its contribution to the interindividual differences in drug response is reviewed here highlighting its role in the kinetics of antipsychotic drugs and the occurrence of drug interactions. The activity of CYP2D6 is inherited as a monogenetic trait and the CYP2D6 gene appears highly polymorphic in humans. The polymorphic...

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Source

Identifiers

PMID: 17168842
DOI: 10.2174/138945006779025329

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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