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Article

CYP2D6 polymorphisms and their influence on risperidone treatment

1 Dec 2016

Abstract excerpt

Abstract: Cytochrome P450 enzyme especially CYP2D6 plays a major role in biotransformation. The interindividual variations of treatment response and toxicity are influenced by the polymorphisms of this enzyme. This review emphasizes the effect of CYP2D6 polymorphisms in risperidone treatment in terms of basic knowledge, pharmacogenetics, effectiveness, adverse events, and clinical practice. Although the previous...

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PMID: 27942231
DOI: 10.2147/pgpm.s107772

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