Article
CYP2D6 variation, behaviour and psychopathology: implications for pharmacogenomics-guided clinical trials.
British journal of clinical pharmacology - 1 Apr 2014
Peñas-Lledó Eva M, Llerena Adrián
Abstract excerpt
Individual and population differences in polymorphic cytochrome P450 enzyme function have been known for decades. The biological significance of these differences has now been deciphered with regard to drug metabolism, action and toxicity as well as disposition of endogenous substrates, including...
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