Article
[Molecular genetic characterization of chronic lymphocytic leukemia aggressivity in Czech patients: a nucleotide variability of genes coding for heavy chain of immunoglobulin].
Casopis lekaru ceskych - 1 Jan 2006
Kuhrová V, Francová H, Klimesová D, Brychtová Y, Doubek M, Trbusek M, Brejcha M, Dvoráková D, Mayer J
Abstract excerpt
BACKGROUND: Chronic lymphocytic leukemia is a heterogeneous disease manifesting with a variable clinical course. It is evident from many studies, that the division into two main prognostic categories is possible on the basis of mutation status of the immunoglobulin heavy-chain gene. The objective of our work was to identify a presence or absence of IgVH gene mutations in B-CLL patients which are monitored or...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.