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Article

Comprehensive characterization of immunoglobulin gene rearrangements in patients with chronic lymphocytic leukaemia.

Journal of cellular and molecular medicine - 1 Jun 2014

René Céline, Prat Nathalie, Thuizat Audrey, Broctawik Mélanie, Avinens Odile, Eliaou Jean-François

Abstract excerpt

Previous studies have suggested a geographical pattern of immunoglobulin rearrangement in chronic lymphocytic leukaemia (CLL), which could be as a result of a genetic background or an environmental antigen. However, the characteristics of Ig rearrangements in the population from the South of France have not yet been established. Here, we studied CLL B-cell repertoire and mutational pattern in a Southern French...

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Share to DNA, Neoplasm
Share to Gene Rearrangement

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Immunoglobulin

Share to Immunoglobulin Heavy Chains

Share to Immunoglobulin J-Chains

Share to Immunoglobulin Variable Region

Share to Leukemia, Lymphocytic, Chronic, B-Cell

Share to Real-Time Polymerase Chain Reaction

Source

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Identifiers

PMID: 24725733
DOI: 10.1111/jcmm.12215
PMCID: PMC4508139

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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