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Article

Human prostacyclin receptor structure and function from naturally-occurring and synthetic mutations.

Prostaglandins & other lipid mediators - 1 Jan 2007

Stitham Jeremiah, Arehart Eric J, Gleim Scott R, Douville Karen L, Hwa John

Abstract excerpt

Prostacyclin (PGI2) is released by vascular endothelial cells and serves as a potent vasodilator, inhibitor of platelet aggregation (anti-thrombotic), and moderator of vascular smooth muscle cell proliferation-migration-differentiation (anti-atherosclerotic). These actions are mediated via a seven transmembrane-spanning G-protein coupled receptor (GPCR), known as the human prostacyclin receptor or hIP. Animal...

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Identifiers

PMID: 17164137
DOI: 10.1016/j.prostaglandins.2006.05.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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