Article

Rare Loss-of-function Mutations of<i>PTGIR</i>Identified in Fibromuscular Dysplasia and Spontaneous Coronary Artery Dissection

2019-11-27

Abstract excerpt

<h4>Background</h4> Fibromuscular Dysplasia (FMD) and Spontaneous Coronary Artery Dissection (SCAD) are related, non-atherosclerotic arterial diseases mainly affecting middle-aged women. Little is known about their physiopathological mechanisms. <h4>Objectives</h4> We aimed to identify rare genetic causes to elucidate molecular mechanisms implicated in FMD and SCAD. <h4>Methods</h4> We analyzed 29 exomes that incl...

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Literature Corpus work: d819558f-4d10-5ad3-b2d0-59bd051a0c28
DOI: 10.1101/19012484

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