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Article

Comprehensive biochemical analysis of rare prostacyclin receptor variants: study of association of signaling with coronary artery obstruction.

The Journal of biological chemistry - 4 Mar 2011

Stitham Jeremiah, Arehart Eric, Elderon Larkin, Gleim Scott R, Douville Karen, Kasza Zsolt, Fetalvero Kristina, MacKenzie Todd, Robb John, Martin Kathleen A, Hwa John

Abstract excerpt

Currently, pharmacogenetic studies are at an impasse as the low prevalence (<2%) of most variants hinder their pharmacogenetic analysis with population sizes often inadequate for sufficiently powered studies. Grouping rare mutations by functional phenotype rather than mutation site can potentiall...

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Identifiers

PMID: 21189259
DOI: 10.1074/jbc.M110.124933
PMCID: PMC3044963

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21189259-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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