Article
Human prostacyclin receptor.
Vitamins and hormones - 1 Jan 2002
Smyth Emer M, FitzGerald Garret A
Abstract excerpt
Prostacyclin, a member of the eicosanoid family of lipid mediators, is the major product of arachidonic acid metabolism formed in the marcovascular endothelium. It is a potent vasodilator, antithrombotic, and antiplatelet agent that mediates it effects through a membrane-associated receptor termed the IP. Cloning of the cDNA for IP, from human and other species, indicated its membership of the G protein-coupled...
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