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Article

Nicotine metabolism and CYP2A6 activity in a population of black African descent: impact of gender and light smoking.

Drug and alcohol dependence - 15 Jun 2007

Mwenifumbo Jill C, Sellers Edward M, Tyndale Rachel F

Abstract excerpt

Genetic variation in CYP2A6 (the main nicotine metabolizing enzyme) accounts for some, but not all, of the interindividual and interethnic variability in the rates of nicotine metabolism. We conducted a nicotine kinetic study in smokers and nonsmokers of black African descent (N=190), excluding those with common genetic variants in CYP2A6, to investigate the association of demographic variables with CYP2A6...

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Source

Identifiers

PMID: 17161559
DOI: 10.1016/j.drugalcdep.2006.11.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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