Article
Effects of different culture protocols on the expression of discrete T-cell receptor variable regions in human tumour infiltrating lymphocytes.
European journal of cancer (Oxford, England : 1990) - 1 Jan 1993
Filgueira L, Zuber M, Merlo A, Harder F, Heberer M, Spagnoli G C
Abstract excerpt
Therapeutic effects of tumour infiltrating lymphocytes (TIL) rely on T-cell receptor (TCR) engagement. In this work, the expression of five TCR alpha/beta variable (V) domains was quantitatively analysed by means of a panel of monoclonal antibodies (Mab) recognising gene products from TCR V alpha...
Topics
- Aged
- Antigens, Tumor-Associated, Carbohydrate
- Cells, Cultured
- Colorectal Neoplasms
- Cytotoxicity, Immunologic
- Female
- Humans
- Immunoglobulin Variable Region
- Kidney Neoplasms
- Lymphocytes, Tumor-Infiltrating
- Male
- Melanoma
- Middle Aged
- Phenotype
- Receptors, Antigen, T-Cell, alpha-beta