Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

IRF5 rs2004640-T allele, the new genetic factor for systemic lupus erythematosus, is not associated with rheumatoid arthritis.

Annals of the rheumatic diseases - 1 Jun 2007

Garnier Sophie, Dieudé Philippe, Michou Laetitia, Barbet Sandra, Tan Alice, Lasbleiz Sandra, Bardin Thomas, Prum Bernard, Cornélis François

Abstract excerpt

BACKGROUND: Recently, a new genetic factor within the interferon regulatory factor 5 (IRF5) gene was demonstrated for systemic lupus erythematosus (SLE) through linkage and association: the rs2004640-T allele. IRF5 is involved in the production of rheumatoid arthritis (RA) cytokines, and SLE alre...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Arthritis, Rheumatoid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Linkage

Share to Genetic Predisposition to Disease

Share to Genotype

Share to Interferon Regulatory Factors

Share to Linkage Disequilibrium

Share to Lupus Erythematosus, Systemic

Source

Open in PubMed Open full text

Identifiers

PMID: 17158136
DOI: 10.1136/ard.2006.061390
PMCID: PMC1954661

Genes

PTPN22

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17158136-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

IRF5 rs2004640-T allele, the new genetic factor for systemic lupus erythematosus, is not associated with rheumatoid arthritis.PMID 17158136Read ↗

Association of a common interferon regulatory factor 5 (IRF5) variant with increased risk of systemic lupus erythematosus (SLE).Semantic proximity Read ↗

Analysis of IRF5 gene functional polymorphisms in rheumatoid arthritis.Semantic proximity Read ↗

The systemic lupus erythematosus IRF5 risk haplotype is associated with systemic sclerosis.Semantic proximity Read ↗

A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus.Semantic proximity Read ↗

Variants in the interferon regulatory factor 5 gene confer genetic risk for systemic lupus erythematosus in a Han Chinese population.Semantic proximity Read ↗

The IRF5 rs2004640 (G/T) polymorphism is not a genetic risk factor for systemic lupus erythematosus in population from south India.Semantic proximity Read ↗

Association between the rs2004640 functional polymorphism of interferon regulatory factor 5 and systemic lupus erythematosus: a meta-analysis.Semantic proximity Read ↗

Association between the IRF5 rs2004640 functional polymorphism and systemic sclerosis: a new perspective for pulmonary fibrosis.Semantic proximity Read ↗

Replication of GWAS-identified systemic lupus erythematosus susceptibility genes affirms B-cell receptor pathway signalling and strengthens the role of IRF5 in disease susceptibility in a Northern European population.Semantic proximity Read ↗

Evidence for genetic association and interaction between the TYK2 and IRF5 genes in systemic lupus erythematosus.Semantic proximity Read ↗

Association of a functional polymorphism in the IRF5 region with systemic sclerosis in a Japanese population.Semantic proximity Read ↗

A functionally relevant IRF5 haplotype is associated with reduced risk to Wegener's granulomatosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.