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Article

Modelling of circadian rhythms in Drosophila incorporating the interlocked PER/TIM and VRI/PDP1 feedback loops.

Journal of theoretical biology - 21 Mar 2007

Xie Z, Kulasiri D

Abstract excerpt

Circadian rhythms of gene activity, metabolism, physiology and behaviour are observed in all the eukaryotes and some prokaryotes. In this study, we present a model to represent the transcriptional regulatory network essential for the circadian rhythmicity in Drosophila. The model incorporates the transcriptional feedback loops revealed so far in the network of the circadian clock (PER/TIM and VRI/PDP1 loops)....

Topics

Animals
Circadian Rhythm
Computer Simulation
Drosophila
Feedback, Physiological
Genes, Insect
Models, Genetic
Mutation
Photic Stimulation
Promoter Regions, Genetic
RNA, Messenger

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Transcription Factors

Transcription, Genetic

Source

Identifiers

PMID: 17157878
DOI: 10.1016/j.jtbi.2006.10.028

Genes

PDP1

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