Article
Development and validation of computational models for mammalian circadian oscillators.
Omics : a journal of integrative biology - 1 Jan 2003
Forger Daniel B, Dean Dennis A, Gurdziel Katherine, Leloup Jean-Christophe, Lee Choogon, Von Gall Charlotte, Etchegaray Jean-Pierre, Kronauer Richard E, Goldbeter Albert, Peskin Charles S, Jewett Megan E, Weaver David R
Abstract excerpt
Circadian rhythms are endogenous rhythms with a cycle length of approximately 24 h. Rhythmic production of specific proteins within pacemaker structures is the basis for these physiological and behavioral rhythms. Prior work on mathematical modeling of molecular circadian oscillators has focused on the fruit fly, Drosophila melanogaster. Recently, great advances have been made in our understanding of the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.