Article
Data assimilation constrains new connections and components in a complex, eukaryotic circadian clock model.
Molecular systems biology - 21 Sept 2010
Pokhilko Alexandra, Hodge Sarah K, Stratford Kevin, Knox Kirsten, Edwards Kieron D, Thomson Adrian W, Mizuno Takeshi, Millar Andrew J
Abstract excerpt
Circadian clocks generate 24-h rhythms that are entrained by the day/night cycle. Clock circuits include several light inputs and interlocked feedback loops, with complex dynamics. Multiple biological components can contribute to each part of the circuit in higher organisms. Mechanistic models with morning, evening and central feedback loops have provided a heuristic framework for the clock in plants, but were...
Topics
- Arabidopsis
- Arabidopsis Proteins
- Circadian Clocks
- Gene Expression Regulation, Plant
- Genes, Plant
- Models, Biological
- Models, Genetic
- Mutation
- Photoperiod
- Protein Biosynthesis