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Article

Growth factor‐independent 1B gene (<i>GFI1B</i>) is overexpressed in erythropoietic and megakaryocytic malignancies and increases their proliferation rate

8 Dec 2006

Abstract excerpt

Growth factor-independent 1B (GFI1B) is a transcription factor essential for the development and differentiation of erythroid and megakaryocytic lineages. We evaluated the GFI1B expression in erythroleukaemia and megakaryocytic leukaemia, as well as in patients with other subtypes of acute myeloid leukaemia (AML), acute lymphoblastic leukaemia (ALL), chronic myeloid leukaemia (CML), myelodysplastic syndrome...

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PMID: 17156408
DOI: 10.1111/j.1365-2141.2006.06407.x

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