Article
Three-dimensional folding of Tetrahymena thermophila rRNA IVS sequence: a proposal.
Journal of biomolecular structure & dynamics - 1 Apr 1991
Benedetti G, Morosetti S
Abstract excerpt
We studied the Tetrahymena thermophila rRNA IVS sequence with the aim of obtaining a model of the structure characterized by the bases proximity of the self-reactions sites. The considered sequence kept up those fragments essential for its catalytic activity as demonstrated by deletion mutants. The first step was the theoretical analysis with a computer method previously proposed, to find optimal free energy...
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