Article
Function of P11, a tertiary base pairing in self-splicing introns of subgroup IA.
Journal of molecular biology - 20 Oct 1991
Jaeger L, Westhof E, Michel F
Abstract excerpt
There is phylogenetic evidence for the existence of a new pairing in subgroup IA1 self-splicing introns. This tertiary interaction, called P11, which is extraneous to the catalytic centre of these ribozymes was modelled after a "pseudoknot" and grafted by computer modelling on the common core structure of group I introns that was recently proposed by Michel & Westhof. In order to probe the function of the P11...
Topics
- Base Composition
- Base Sequence
- DNA, Mitochondrial
- DNA, Ribosomal
- Introns
- Kinetics
- Macromolecular Substances
- Magnesium Chloride
- Models, Molecular
- Molecular Sequence Data
- Mutagenesis, Site-Directed
