Article
Dimers of Thermus thermophilus elongation factor Ts are required for its function as a nucleotide exchange factor of elongation factor Tu.
European journal of biochemistry - 1 Jul 1998
Nesper M, Nock S, Sedlák E, Antalík M, Podhradský D, Sprinzl M
Abstract excerpt
Elongation factor Ts (EF-Ts) promotes the formation of active GTP-bound elongation factor Tu (EF-Tu) by accelerating the dissociation of GDP from the EF-Tu x GDP complex. Thermus thermophilus EF-Ts forms a dimer in solution, which is stabilised by interaction of a three-stranded antiparallel beta...
Topics
- Bacterial Proteins
- Calorimetry
- Circular Dichroism
- Dimerization
- Guanosine Diphosphate
- Hot Temperature
- Mutation
- Peptide Chain Elongation, Translational
- Peptide Elongation Factor Tu
- Peptide Elongation Factors
- Protein Binding
- Protein Denaturation
- Protein Structure, Secondary
- Thermodynamics
- Thermus thermophilus