Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Design of base-discriminating fluorescent (BDF) nucleobase for SNP typing.

Nucleic acids symposium series (2004) - 1 Jan 2004

Saito Yoshio, Kanatani Keiichiro, Ochi Yuji, Okamoto Akimitsu, Saito Isao

Abstract excerpt

We have devised novel pyrene-labeled BDF nucleosides, (Py)U, (Py)C, (Py)deazaA, and (Py)A. BDF probes containing these fluorescent nucleosides selectively emit fluorescence only when the base opposite the BDF base is a target base. Oligonucleotides containing these BDF nucleosides act as effective reporter probes for homogeneous SNP typing of DNA samples.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Fluorescent Dyes
Share to Genes, BRCA2
Share to Oligonucleotide Probes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Single Nucleotide

Share to Spectrometry, Fluorescence

Source

Identifiers

PMID: 17150569
DOI: 10.1093/nass/48.1.243

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Design of base-discriminating fluorescent (BDF) nucleobase for SNP typing.PMID 17150569Read ↗

Pyrene-labeled base-discriminating fluorescent DNA probes for homogeneous SNP typing.Semantic proximity Read ↗

Synthesis and properties of novel base-discriminating fluorescent (BDF) nucleosides.Semantic proximity Read ↗

Design of dual-labeled oligonucleotide probes for SNPs genotyping.Semantic proximity Read ↗

Design of base-discriminating fluorescent nucleoside and its application to t/c SNP typing.Semantic proximity Read ↗

Simple SNP typing assay using a base-discriminating fluorescent probe.Semantic proximity Read ↗

SNPs typing by base-discriminating fluorescence DNA probe.Semantic proximity Read ↗

Clear distinction of purine bases on the complementary strand by a fluorescence change of a novel fluorescent nucleoside.Semantic proximity Read ↗

Fluorescent detection of single nucleotide polymorphism utilizing a hairpin DNA containing a nucleotide base analog pyrrolo-deoxycytidine as a fluorescent probe.Semantic proximity Read ↗

Dual-labeled oligonucleotide probe for sensing adenosine via FRET: a novel alternative to SNPs genotyping.Semantic proximity Read ↗

Homoadenine signalling system for SNP typing.Semantic proximity Read ↗

Fluorescence detection of single-nucleotide polymorphism with single-strand triplex-forming DNA probes.Semantic proximity Read ↗

Universal SNP genotyping assay with fluorescence polarization detection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.