Article
Universal SNP genotyping assay with fluorescence polarization detection.
BioTechniques - 1 Sept 2001
Hsu T M, Chen X, Duan S, Miller R D, Kwok P Y
Abstract excerpt
The degree of fluorescence polarization (FP) of a fluorescent molecule is a reflection of its molecular weight (Mr). FP is therefore a useful detection methodfor homogeneous assays in which the starting reagents and products differ significantly in Mr. We have previously shown that FP is a good detection method for the single-base extension and the 5'-nuclease assays. In this report, we describe a universal,...
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