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Article

Design of base-discriminating fluorescent nucleoside and its application to t/c SNP typing.

Journal of the American Chemical Society - 6 Aug 2003

Okamoto Akimitsu, Tanaka Kazuo, Fukuta Tetsuo, Saito Isao

Abstract excerpt

We report a novel method for base detection using a base-discriminating fluorescent (BDF) nucleoside. We developed BDF probes containing methoxybenzodeazaadenine MDA and methoxybenzodeazainosine MDI, which give strong fluorescence only when the base on the complementary strand is cytosine and thymine, respectively. Thus, the MDA- and MDI-containing ODNs can be used as a very effective BDF probe for the detection...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12889950
DOI: 10.1021/ja035408l

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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