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Article

Synthetic signal sequences that enable efficient secretory protein production in the yeast Kluyveromyces marxianus.

Microbial cell factories - 14 Feb 2015

Yarimizu Tohru, Nakamura Mikiko, Hoshida Hisashi, Akada Rinji

Abstract excerpt

BACKGROUND: Targeting of cellular proteins to the extracellular environment is directed by a secretory signal sequence located at the N-terminus of a secretory protein. These signal sequences usually contain an N-terminal basic amino acid followed by a stretch containing hydrophobic residues, although no consensus signal sequence has been identified. In this study, simple modeling of signal sequences was...

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Identifiers

PMID: 25889890
DOI: 10.1186/s12934-015-0203-y
PMCID: PMC4347551

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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