Article
LdCompare: rapid computation of single- and multiple-marker r2 and genetic coverage.
Bioinformatics (Oxford, England) - 15 Jan 2007
Hao K, Di X, Cawley S
Abstract excerpt
UNLABELLED: The scale of genetic-variation datasets has increased enormously and the linkage equilibrium (LD) structure of these polymorphisms, particularly in whole-genome association studies, is of great interest. The significant computational complexity of calculating single- and multiple-marker correlations at a genome-wide scale remains challenging. We have developed a program that efficiently characterizes...
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