Article
Fast and efficient QTL mapper for thousands of molecular phenotypes.
Bioinformatics (Oxford, England) - 15 May 2016
Ongen Halit, Buil Alfonso, Brown Andrew Anand, Dermitzakis Emmanouil T, Delaneau Olivier
Abstract excerpt
MOTIVATION: In order to discover quantitative trait loci, multi-dimensional genomic datasets combining DNA-seq and ChiP-/RNA-seq require methods that rapidly correlate tens of thousands of molecular phenotypes with millions of genetic variants while appropriately controlling for multiple testing. RESULTS: We have developed FastQTL, a method that implements a popular cis-QTL mapping strategy in a user- and...
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