Article
The chemokine (C-C-motif) receptor 3 (CCR3) gene is linked and associated with age at menarche in Caucasian females.
Human genetics - 1 Mar 2007
Yang Fang, Xiong Dong-hai, Guo Yan, Shen Hui, Xiao Peng, Zhang Feng, Jiang Hui, Recker Robert R, Deng Hong-wen
Abstract excerpt
Chemokine (C-C-motif) receptor 3 (CCR3), playing an important role in endometrium related metabolic pathways, may influence the onset of menarche. To test linkage and/or association between CCR3 polymorphisms with the variation of age at menarche (AAM) in Caucasian females, we recruited a sample of 1,048 females from 354 Caucasian nuclear families and genotyped 16 SNPs spanning the entire CCR3 gene. Linkage...
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