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Article

Three common variants of LEP, NPY1R and GPR54 show no association with age at menarche.

Hormone research - 1 Jan 2009

Rothenbuhler Anya, Lotton Chantal, Fradin Delphine

Abstract excerpt

CONTEXT: Twin and family studies indicate a significant heritability of pubertal timing and more specifically of age at menarche (AAM). OBJECTIVE: Test the association of AAM with common variants of three candidate genes suspected to have a prominent role in reproductive physiology: leptin (LEP), neuropeptide Y receptor 1 (NPY1R) and GPR54. DESIGN AND METHODS: We selected the -2459 LEP, the rs7687423 NPY1R and...

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Source

Identifiers

PMID: 19506390
DOI: 10.1159/000223417

Genes

LEP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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