Article
Effects of eicosapentaenoic acid on the early stage of type 2 diabetic nephropathy in KKA(y)/Ta mice: involvement of anti-inflammation and antioxidative stress.
Metabolism: clinical and experimental - 1 Dec 2006
Zhang Minfang, Hagiwara Shinji, Matsumoto Masukazu, Gu Leyi, Tanimoto Mitsuo, Nakamura Shinji, Kaneko Shigeru, Gohda Tomohito, Qian Jiaqi, Horikoshi Satoshi, Tomino Yasuhiko
Abstract excerpt
Eicosapentaenoic acid (EPA) has been reported to have beneficial effects on the progression of various renal diseases including diabetic nephropathy; however, the precise mechanisms are not completely understood. We examined the effects of EPA on the early stage of type 2 diabetic nephropathy in KKA(y)/Ta mice and the possible role of inflammation, oxidative stress, and growth factor in this process. KKA(y)/Ta...
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