Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effect of pioglitazone on the early stage of type 2 diabetic nephropathy in KK/Ta mice.

Metabolism: clinical and experimental - 1 Nov 2004

Tanimoto Mitsuo, Fan Qiuling, Gohda Tomohito, Shike Toshihide, Makita Yuichiro, Tomino Yasuhiko

Abstract excerpt

Pioglitazone (PIO) has preventive effects on impaired glucose tolerance (IGT) and urinary albumin excretion in diabetes. These effects in the early stage of diabetic nephropathy have not been fully described. Endothelial constitutive nitric oxide synthase (ecNOS) might be one of the mechanisms of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Albuminuria
Share to Creatinine
Share to Kidney Glomerulus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Nitric Oxide Synthase

Share to Nitric Oxide Synthase Type II

Share to Pioglitazone

Share to Serum Albumin

Share to Thiazolidinediones

Source

Identifiers

PMID: 15536604
DOI: 10.1016/j.metabol.2004.06.016

Genes

ACR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15536604-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effect of pioglitazone on the early stage of type 2 diabetic nephropathy in KK/Ta mice.PMID 15536604Read ↗

Effects of eicosapentaenoic acid on the early stage of type 2 diabetic nephropathy in KKA(y)/Ta mice: involvement of anti-inflammation and antioxidative stress.Semantic proximity Read ↗

Periostin deficiency attenuates kidney fibrosis in diabetic nephropathy via improving pancreatic β-cell dysfunctionSemantic proximity Read ↗

Canagliflozin reverses Th1/Th2 imbalance and promotes podocyte autophagy in rats with membranous nephropathySemantic proximity Read ↗

Pentoxifylline Ameliorates Subclinical Atherosclerosis Progression in Patients with Type 2 Diabetes and Chronic Kidney Disease: A Randomized Pilot TrialSemantic proximity Read ↗

Role of endothelial nitric oxide synthase in diabetic nephropathy: lessons from diabetic eNOS knockout mice.Semantic proximity Read ↗

Loss of ACE2 accelerates time-dependent glomerular and tubulointerstitial damage in streptozotocin-induced diabetic mice.Semantic proximity Read ↗

Diabetic kidney disease in FVB/NJ Akita mice: temporal pattern of kidney injury and urinary nephrin excretion.Semantic proximity Read ↗

Assessment of diabetic nephropathy in the Akita mouse.Semantic proximity Read ↗

Podocyte-specific knockout of cyclooxygenase 2 exacerbates diabetic kidney disease.Semantic proximity Read ↗

Protective Effects of <em>Phyllanthus emblica</em> L. Extract against Renal Dysfunction, Angiogenesis, and Fibrosis Occur through the Regulation of PKCα Activation, Vegf, and TGF-β1 in a Diabetic Nephropathy ModelSemantic proximity Read ↗

Identification of quantitative trait loci for diabetic nephropathy in KK-Ay/Ta mice.Semantic proximity Read ↗

Serum Pentosidine Levels Are Associated with Early Declines in Estimated Glomerular Filtration Rate, Independent of Glycemic Status: A Cross-Sectional Analysis from the Fukuoka Epidemiological Study of AtherosclerosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.