Article

Epac ameliorates tubulointerstitial inflammation in diabetic nephropathy via C/EBPβ/SOCS3/STAT3 pathway

2020-02-26

Abstract excerpt

<h4>Background: </h4> Tubulointerstitial inflammation plays a pivotal role in the progression of diabetic nephrology (DN), and tubular cells act as the driving force in the inflammation cascade. The aim of the study is to investigate whether activation of Epac alleviates tubulointerstitial inflammation through SOCS3/JAK/STAT3 pathway under DN. <h4>Methods:</h4> The kidney morphological changes and the level of oxi...

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Identifiers and source

Literature Corpus work: 79844971-ade4-54cc-98b3-4a49d657f3fc
DOI: 10.21203/rs.2.24571/v1

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