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Article

The aryl hydrocarbon receptor-dependent deregulation of cell cycle control induced by polycyclic aromatic hydrocarbons in rat liver epithelial cells.

Mutation research - 3 Feb 2007

Andrysík Zdenek, Vondrácek Jan, Machala Miroslav, Krcmár Pavel, Svihálková-Sindlerová Lenka, Kranz Anne, Weiss Carsten, Faust Dagmar, Kozubík Alois, Dietrich Cornelia

Abstract excerpt

Disruption of cell proliferation control by polycyclic aromatic hydrocarbons (PAHs) may contribute to their carcinogenicity. We investigated role of the aryl hydrocarbon receptor (AhR) in disruption of contact inhibition in rat liver epithelial WB-F344 'stem-like' cells, induced by the weakly mutagenic benz[a]anthracene (BaA), benzo[b]fluoranthene (BbF) and by the strongly mutagenic benzo[a]pyrene (BaP). There...

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Identifiers

PMID: 17141280
DOI: 10.1016/j.mrfmmm.2006.10.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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