Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Impairment of cell cycle progression by aflatoxin B1 in human cell lines.

Mutagenesis - 1 May 2002

Ricordy R, Gensabella G, Cacci E, Augusti-Tocco G

Abstract excerpt

Aflatoxin B1 is a mycotoxin produced by Aspergillus flavus and Aspergillus parasiticum, which may be present as a food contaminant. It is known to cause acute toxic effects and act as a carcinogenic agent. The carcinogenic action has been related to its ability to form unstable adducts with DNA, which represent possible mutagenic sites. On the other hand, the primary cellular target responsible for its toxic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aflatoxin B1
Share to Bromodeoxyuridine
Share to Carcinogens

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Cycle

Share to Cyclic AMP

Share to Flow Cytometry

Share to Multivariate Analysis

Share to Proto-Oncogene Proteins p21(ras)

Source

Identifiers

PMID: 11971996
DOI: 10.1093/mutage/17.3.241

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Impairment of cell cycle progression by aflatoxin B1 in human cell lines.PMID 11971996Read ↗

Aflatoxin genotoxicity is associated with a defective DNA damage response bypassing p53 activation.Semantic proximity Read ↗

Aflatoxin B1-induced immortalization of cultured skin fibroblasts from a patient with Li-Fraumeni syndrome.Semantic proximity Read ↗

Aflatoxin B1-induced DNA adduct formation and p53 mutations in CYP450-expressing human liver cell lines.Semantic proximity Read ↗

Analysis of Cell Cycle Disruptions in Cultures of Rat Pleural Mesothelial Cells Exposed to Asbestos FibersSemantic proximity Read ↗

Hydrocarbon carcinogens evade cellular defense mechanism of G1 arrest in nontransformed and malignant lung cell lines.Semantic proximity Read ↗

Chromosome instability in human hepatocellular carcinoma depends on p53 status and aflatoxin exposureSemantic proximity Read ↗

Global genomic changes induced by two-stage carcinogen exposure are precancerous alterations in non-transformed human liver epithelial THLE-3 cells.Semantic proximity Read ↗

The food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine activates S-phase checkpoint and apoptosis, and induces gene mutation in human lymphoblastoid TK6 cells.Semantic proximity Read ↗

Chlorophyllin attenuates the effects of benzo[a]pyrene in human hepatoma HepG2/C3A cellsSemantic proximity Read ↗

Cellular interactions and metabolism of aflatoxin: an update.Semantic proximity Read ↗

The mycotoxin aflatoxin B1 stimulates Epstein–Barr virus-induced B-cell transformation in in vitro and in vivo experimental modelsSemantic proximity Read ↗

Induction of ouabain-resistance mutation and cycle-dependent transformation of C3H/10T1/2 cells by N-nitroso-2-acetylaminofluorene.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.