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Article

Characterization of glomerular cell phenotypes following repeated cycles of benzo[a]pyrene injury in vitro.

Biochemical pharmacology - 1 Jul 2002

Parrish Alan R, Alejandro Napoleon F, Bral Christopher M, Kevin Kerzee J, Bowes Russell C, Ramos Kenneth S

Abstract excerpt

Exposure of cultured glomeruli to benzo[a]pyrene (BaP), a carcinogenic hydrocarbon, modulates mesangial and visceral epithelial cell proliferation in vivo and in vitro. The present studies were conducted to characterize mitogenic signaling profiles of cultured glomeruli following repeated cycles of BaP challenge. Enhanced rates of DNA synthesis were observed by the third passage in randomly cycling cultures after...

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PMID: 12106603
DOI: 10.1016/s0006-2952(02)01054-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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