Article
Phase I and Phase II enzyme polymorphisms and childhood cancer.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research - 1 Sept 2006
Swinney Ryan, Hsu Stephanie, Tomlinson Gail
Abstract excerpt
Childhood cancers continue to be challenging clinical entities whose etiology, demographic characteristics, clinical progression, treatment efficacy, and outcomes remain incompletely understood. Research suggests that multiple environmental and genetic factors may play crucial roles in the pathophysiology of many of these malignancies. Recent attention has been directed to the role of carcinogen metabolizing...
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