Article
Genetic polymorphisms and metabolism of endocrine disruptors in cancer susceptibility.
Cadernos de saude publica - 1 Jan 2000
Hatagima Ana
Abstract excerpt
Epidemiological studies have estimated that approximately 80% of all cancers are related to environmental factors. Individual cancer susceptibility can be the result of several host factors, including differences in metabolism, DNA repair, altered expression of tumor suppressor genes and proto-oncogenes, and nutritional status. Xenobiotic metabolism is the principal mechanism for maintaining homeostasis during...
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