Article
Cancer and molecular biomarkers of phase 2.
Methods in enzymology - 1 Jan 2005
Dalhoff Kim, Buus Jensen Kaspar, Enghusen Poulsen Henrik
Abstract excerpt
Associations between genotypes of phase 2 enzymes and cancer risk are extracted from epidemiological studies, namely case-control studies. Variant alleles in glutathione S-transferase (GST), UDP-glucuronosyltransferase (UGT), sulfotransferase (SULT), and N-acetyltransferase (NAT) have been used as molecular genetic biomarkers of risk. GSTM(my)1 has been associated with an increased risk of colorectal cancer, lung...
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