Article
Polymorphism of CYP450 and cancer susceptibility.
Acta pharmacologica Sinica - 1 Aug 2000
Han X M, Zhou H H
Abstract excerpt
CYP450s form a superfamily involved in the metabolism of many endogenous and exogenous substrates. In this review, the substrates, probe drugs, genetic polymorphisms, and associated cancers of CYP1A1, CYP1A2, CYP2C19, CYP2D6, CYP2E1, and CYP3A4 are summarized.
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