Article
Human Cytochrome P450 Cancer-Related Metabolic Activities and Gene Polymorphisms
2024-10-29
Abstract excerpt
Human CYP1-CYP4 families play crucial roles in the biosynthesis, bioactivation, and detoxification of a diverse range of chemicals including xenobiotics, steroid hormones, vitamins, bile acids, procarcinogens, and drugs. The same CYP isoform can be involved in the conversion of different substrates via both bioactivation and detoxification reactions depending on a substrate type. Furthermore, the same CYP isoform...
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Identifiers and source
- Literature Corpus work
- 4c92d916-dc81-5614-bc3d-d9b03b55a444
- DOI
- 10.20944/preprints202410.2261.v1
