Article
Generation of conditional Cited2 null alleles.
Genesis (New York, N.Y. : 2000) - 1 Dec 2006
Preis Jost I, Wise Natalie, Solloway Mark J, Harvey Richard P, Sparrow Duncan B, Dunwoodie Sally L
Abstract excerpt
Cited2 is a transcriptional co-factor that is widely expressed in both embryonic and extraembryonic cells during early development. It is essential for embryonic development with Cited2 null embryos showing abnormal development of organs including heart, neural tube, adrenal glands, and placenta (both in trophoblast derivatives and invading fetal vasculature), as well as having defects in the establishment of the...
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