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Article

Allelic variants of ABC drug transporter Cdr1p in clinical isolates of Candida albicans.

Biochemical and biophysical research communications - 12 Jan 2007

Haque Absarul, Rai Versha, Bahal Birendra Singh, Shukla Shipra, Lattif Ali Abdul, Mukhopadhyay Gauranga, Prasad Rajendra

Abstract excerpt

Candida drug resistance protein (Cdr1p) is a major drug efflux protein, which plays a key role in commonly encountered clinical azole resistance in Candida albicans. We have analyzed its sequence in several azole resistant clinical isolates to evaluate the allelic variation within CDR1 gene and to relate it to its functional activity. The sequence analysis revealed 53 single nucleotide polymorphisms (SNPs), out...

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PMID: 17126815
DOI: 10.1016/j.bbrc.2006.11.035

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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