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Article

Allele-specific histone modifications regulate expression of the Dlk1-Gtl2 imprinted domain.

Genomics - 1 Feb 2007

Carr Michael S, Yevtodiyenko Aleksey, Schmidt Claudia L, Schmidt Jennifer V

Abstract excerpt

Dlk1 and Gtl2 are reciprocally expressed imprinted genes located on mouse chromosome 12. The Dlk1-Gtl2 locus carries three differentially methylated regions (DMRs), which are methylated only on the paternal allele. Of these, the intergenic (IG) DMR, located 12 kb upstream of Gtl2, is required for proper imprinting of linked genes on the maternal chromosome, while the Gtl2 DMR, located across the promoter of the...

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Source

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Identifiers

PMID: 17126526
DOI: 10.1016/j.ygeno.2006.10.005
PMCID: PMC1802099

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Allele-specific histone modifications regulate expression of the Dlk1-Gtl2 imprinted domain.PMID 17126526Read ↗

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