Article
Restricted co-expression of Dlk1 and the reciprocally imprinted non-coding RNA, Gtl2: implications for cis-acting control.
Developmental biology - 15 Jun 2007
da Rocha Simão T, Tevendale Maxine, Knowles Edward, Takada Shuji, Watkins Marie, Ferguson-Smith Anne C
Abstract excerpt
Dlk1 and Gtl2 are reciprocally imprinted neighboring genes located within a 1 Mb imprinted domain on murine distal chromosome 12. The two genes are expressed and developmentally regulated during mammalian embryogenesis. Dlk1/Pref1 encodes a transmembrane protein with homology to members of the Notch/Delta developmental signaling pathway and Gtl2 generates alternatively spliced poly-adenylated transcripts lacking...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
