Expression of mutant p53, c-erbB-2 and the epidermal growth factor receptor in transitional cell carcinoma of the human urinary bladder.

doi:10.1038/bjc.1991.211

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Article

Expression of mutant p53, c-erbB-2 and the epidermal growth factor receptor in transitional cell carcinoma of the human urinary bladder.

British journal of cancer - 1 Jun 1991

Wright C, Mellon K, Johnston P, Lane D P, Harris A L, Horne C H, Neal D E

Abstract excerpt

Expression of the p53, the epidermal growth factor receptor (EGFr; c-erbB-1) and c-erbB-2 proteins was studied in 82 patients with primary transitional cell carcinoma of the bladder using an immuno-histochemical method. Strong or moderate staining was found in 18% of tumours for p53 with weaker s...

Topics

Aged
Biomarkers, Tumor
Carcinoma, Transitional Cell
ErbB Receptors
Female
Gene Expression
Humans
Male
Mutation
Neoplasm Staging
Proto-Oncogene Proteins
Receptor, ErbB-2
Staining and Labeling
Tumor Suppressor Protein p53
Urinary Bladder Neoplasms

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Identifiers

PMID: 1712624
DOI: 10.1038/bjc.1991.211
PMCID: PMC1972558

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1712624-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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