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Article

Inactivation of tumor suppressor genes and deregulation of the c-myc gene in urothelial cancer cell lines.

Urological research - 1 Jan 1995

Grimm M O, Jürgens B, Schulz W A, Decken K, Makri D, Schmitz-Dräger B J

Abstract excerpt

Recent investigations have demonstrated p53 and Rb alterations in a subset of transitional cell carcinoma (TCC). Further genetic changes during tumor progression include overexpression of the c-myc gene in a significant number of mainly invasive bladder tumors. To study the possible interactions...

Topics

Base Sequence
DNA
Gene Expression Regulation
Genes, Tumor Suppressor
Genes, myc
Molecular Probes
Molecular Sequence Data
Mutation
Polymerase Chain Reaction
RNA, Messenger
Retinoblastoma Protein
Tumor Cells, Cultured

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Tumor Suppressor Protein p53

Urologic Neoplasms

Source

Identifiers

PMID: 8839385
DOI: 10.1007/BF00300017

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8839385-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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