Article
KLF6 IVS1 -27G>A variant and the risk of prostate cancer in Finland.
European urology - 1 Oct 2007
Seppälä Eija H, Autio Ville, Duggal Priya, Ikonen Tarja, Stenman Ulf-Håkan, Auvinen Anssi, Bailey-Wilson Joan E, Tammela Teuvo L J, Schleutker Johanna
Abstract excerpt
OBJECTIVES: A recent report demonstrated that KLF6 IVS1 -27G>A substitution increases the transcription of alternatively spliced isoforms; this action was suggested to be associated with prostate cancer (pCA). To evaluate these findings among the Finnish population, a total of 3348 samples were analysed. METHODS: The variant was genotyped in 164 patients with familial pCA, 852 patients with unselected pCA, 459...
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