Article
Study on the SFRP4 gene polymorphism and expression in prostate cancer.
Journal of genetics - 1 Jan 2020
Natarajan Aishwarya, Sudha Bandla Shaile, Damodaran Mohan, Sundaram Sandhya, Venkatesan Vettriselvi
Abstract excerpt
Prostate cancer is a heterogeneous disease and considered to be the most commonly diagnosed cancer. SFRP4 gene acts as Wnt antagonist in the Wnt signalling pathway, thereby playing an important role in carcinogenesis. The aim of the present study was to investigate two single-nucleotide polymorphisms: c.958 C>A (rs1802073) and c.1019 G>A (rs1802074) in the SFRP4 gene and its expression in prostate cancer. A...
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