Article
BRCA1 mutations do not increase prostate cancer risk: results from a meta-analysis including new data.
The Prostate - 1 Dec 2011
Fachal Laura, Gómez-Caamaño Antonio, Celeiro-Muñoz Catuxa, Peleteiro Paula, Blanco Ana, Carballo Ana, Forteza Jerónimo, Carracedo Angel, Vega Ana
Abstract excerpt
BACKGROUND: Although in recent years deleterious BRCA1 mutations have been extensively studied as a prostate cancer risk factor, results are inconclusive. To assess the contribution of the BRCA1 Galician founder mutation c.211A>G in prostate cancer morbidity we conducted a case-control study. Moreover, to better elucidate whether deleterious BRCA1 mutations are involved in the development of prostate cancer, we...
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