Article
Involvement of fibroblast growth factor receptor genes in benign prostate hyperplasia in a Korean population.
Disease markers - 1 Jan 2013
Park Hae Jeong, Kim Su Kang, Kim Jong Woo, Lee Sang Hyub, Yoo Koo Han, Chung Joo-Ho
Abstract excerpt
Fibroblast growth factors (FGFs) and their receptors (FGFRs) have been implicated in prostate growth and are overexpressed in benign prostatic hyperplasia (BPH). In this study, we investigated whether single nucleotide polymorphisms (SNPs) of the FGFR genes (FGFR1 and FGFR2) were associated with BPH and its clinical phenotypes in a population of Korean men. We genotyped four SNPs in the exons of FGFR1 and FGFR2...
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